Subject(s)
Humans , Female , Child , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Young Adult , Rifampin/administration & dosage , Rifampin/analogs & derivatives , Tuberculosis, Pulmonary/drug therapy , Moxifloxacin/administration & dosage , Antibiotics, Antitubercular/administration & dosage , Antitubercular Agents/administration & dosage , Rifampin/adverse effects , Drug Administration Schedule , Randomized Controlled Trials as Topic , Treatment Outcome , Clinical Trials, Phase III as Topic , Drug Therapy, Combination , Moxifloxacin/adverse effects , Duration of Therapy , Antibiotics, Antitubercular/adverse effects , Antitubercular Agents/adverse effectsABSTRACT
Abstract We report a case of a middle-aged woman who developed acute, bilateral, symmetrical, slightly transilluminating depigmentation of the iris and pigment discharge into the anterior chamber following the use of oral moxifloxacin for bacterial sinusitis. She had been misdiagnosed as having autoimmune uveitis, treated with steroids and tropicamide, and underwent severe ocular hypertension and glaucoma despite posterior correct diagnosis.
Resumo Relato de um caso de uma paciente do sexo feminino de meia idade que desenvolveu despigmentação bilateral simultânea aguda com dispersão de pigmentos na câmara anterior e discreta transiluminação após o uso de moxifloxacino oral para tratamento de sinusite bacteriana. Ela Havia sido diagnosticada com uveite autoimune e tratada com corticosteroide tópico e tropicamida e evoluiu com hipertensão ocular grave e glaucoma apesar de ,posteriormente, o diagnóstico ter sido correto.